Unfolding proteins with an atomic force microscope: Force-fluctuation-induced nonexponential kinetics
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چکیده
منابع مشابه
Unfolding proteins with an atomic force microscope: force-fluctuation-induced nonexponential kinetics.
We show that in experimental atomic force microscopy studies of the lifetime distribution of mechanically stressed folded proteins the effects of externally applied fluctuations cannot be distinguished from those of internally present fluctuations. In certain circumstances this leads to artificially nonexponential lifetime distributions, which can be misinterpreted as a signature of protein com...
متن کاملUnfolding protein with an atomic force microscope: Force-fluctuation induced non-exponential kinetics
We show that in experimental atomic force microscopy studies of the lifetime distribution of mechanically stressed folded proteins the effects of externally applied fluctuations can not be distinguished from those of internally present fluctuations. In certain circumstances this leads to artificially non-exponential lifetime distributions which can be misinterpreted as a signature of protein co...
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ژورنال
عنوان ژورنال: Physical Review E
سال: 2011
ISSN: 1539-3755,1550-2376
DOI: 10.1103/physreve.84.041920